@conference {
	title = {A Systems Biology Model Studying the Role of Cholesterol in Alzheimer{\textquoteright}s Disease Progression},
	author = {Kyrtsos, C Rose., Baras, John S.},
	year = {2011},
	month = {10/2011},
	abstract = {A simplified network describing the interactions between the cholesterol and beta amyloid (Aβ) synthesis pathways was generated using information available from literature and the KEGG database. A system of non-linear differential equations was developed and modeled using several different initial conditions. Rate constants were approximated using ratiometric data from the literature, or by fitting parameters to obtain a stable simulation within given biological constraints. Simulations demonstrated the importance of negative feedback control by cholesterol in the regulation of beta-amyloid levels. Additionally, the effect of reduced LRP-1 levels and oscillatory cholesterol generation was studied.},
	address = {Kos Island, Greece},
	booktitle = {10th IEEE International Workshop on Biomedical Engineering (10thBioEng)},
	pages = {pp. 1-7}
}
